Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | EEF2K | O00418 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628324 | 1.00 | CYP2C9 (0.74) | CYP2C9MEN1KMT2AEEF2KSRC | |
| SCHEMBL30682161 | 0.85 | CYP2C9 (1.00) | CYP2C9MEN1KMT2AEEF2KSRC | |
| SCHEMBL6851626 | 0.85 | CYP2C9 (1.00) | CYP2C9MEN1KMT2AEEF2KSRC | |
| SCHEMBL6848698 | 0.85 | CYP2C9 (1.00) | CYP2C9MEN1KMT2AEEF2KSRC | |
| SCHEMBL6853627 | 0.82 | CYP2C9 (0.86) | CYP2C9MEN1KMT2AEEF2KSRC | |
| SCHEMBL6853810 | 0.82 | CYP2C9 (0.86) | CYP2C9MEN1KMT2AEEF2KSRC | |
| SCHEMBL29259516 | 0.79 | MEN1 (0.49) | CYP2C9MEN1KMT2ASRCCYP1A2 | |
| SCHEMBL29259517 | 0.79 | MEN1 (0.49) | CYP2C9MEN1KMT2ASRCCYP1A2 | |
| SCHEMBL28618885 | 0.76 | CYP2C9 (0.64) | CYP2C9MEN1KMT2AEEF2KSRC | |
| SCHEMBL28618884 | 0.76 | CYP2C9 (0.64) | CYP2C9MEN1KMT2AEEF2KSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354577-B | Monocarbonyl curcuminoid compound and preparation method and application thereof | 西南医科大学附属中医医院 | 2022-08-26 | — | — | CN | disclosed |
| CN-113354577-A | Monocarbonyl curcumin analogue and preparation and application thereof | 西南医科大学附属中医医院 | 2021-09-07 | — | — | CN | disclosed |