Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433541 | 1.00 | HCAR2 (0.68) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL28615318 | 1.00 | HCAR2 (0.68) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL28619034 | 1.00 | HCAR2 (0.68) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL28617004 | 1.00 | HCAR2 (0.68) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL28794983 | 1.00 | HCAR2 (0.68) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL1947729 | 0.93 | HCAR2 (0.81) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL9053240 | 0.93 | HCAR2 (0.81) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL12971144 | 0.93 | HCAR2 (0.81) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL560434 | 0.93 | HCAR2 (0.60) | HCAR2ATMHTTMAPTMEN1 | |
| SCHEMBL29483378 | 0.93 | HCAR2 (0.81) | HCAR2ATMHTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705581-B | Silicone rubber composition, silicone rubber and preparation method thereof | 浙江清华柔性电子技术研究院 | 2021-07-13 | — | — | CN | disclosed |