Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 12/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16050639 | 0.82 | KDM5A (0.52) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16047075 | 0.81 | KDM5A (0.49) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16046987 | 0.81 | KDM5A (0.56) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL18159119 | 0.81 | KDM5A (0.53) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16047129 | 0.80 | KDM5A (0.50) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16046199 | 0.79 | KDM5A (0.46) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16046543 | 0.78 | KDM5A (0.50) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16048043 | 0.78 | KDM5A (0.50) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16049130 | 0.77 | KDM5A (0.49) | KDM5AKDM4CPLATKDM4EALDH1A1 | |
| SCHEMBL16048319 | 0.77 | KDM5A (0.49) | KDM5AKDM4CPLATKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980386-B | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2021-08-13 | — | — | CN | disclosed |