Ethylene

Ethylene

SCHEMBL28629154

C=C.C=C.COc1cccc(C=O)c1O

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 8/20 0.93
TLR2 O60603 1/20 0.93
TLR1 Q15399 1/20 0.93
TLR6 Q9Y2C9 1/20 0.93
CA12 O43570 1/20 0.56
KDM4E B2RXH2 3/20 0.54
MAPT P10636 3/20 0.54
LMNA P02545 2/20 0.54
NPC1 O15118 2/20 0.54
POLB P06746 1/20 0.54
HTT P42858 1/20 0.54
RECQL P46063 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MAPK1 P28482 2/20 0.53
ALDH1A1 P00352 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16004 0.96 ERN1 (1.00) ERN1TLR2TLR1TLR6CA12
SCHEMBL929734 0.96 ERN1 (1.00) ERN1TLR2TLR1TLR6CA12
SCHEMBL30485148 0.96 ERN1 (1.00) ERN1TLR2TLR1TLR6CA12
SCHEMBL11407272 0.94 ERN1 (0.96) ERN1TLR2TLR1TLR6CA12
SCHEMBL4450612 0.94 ERN1 (0.96) ERN1TLR2TLR1TLR6CA12
Methylamine SCHEMBL28936774 0.93 ERN1 (0.93) ERN1TLR2TLR1TLR6CA12
SCHEMBL28121343 0.89 ERN1 (0.86) ERN1TLR2TLR1TLR6CA12
Guaiacol SCHEMBL27774547 0.89 ERN1 (0.78) ERN1TLR2TLR1TLR6CA12
SCHEMBL29105898 0.88 ERN1 (0.83) ERN1TLR2TLR1TLR6CA12
Ethylenediamine SCHEMBL9276378 0.88 ERN1 (0.83) ERN1TLR2TLR1TLR6CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106831484-B O-vanillin bis-ethylenediamine vanadium complex, and synthesis method and application thereof 河南中医药大学 2021-09-21 CN disclosed