Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641195 | 0.80 | KDM4E (0.35) | ALDH1A1KDM4E | |
| SCHEMBL16286093 | 0.77 | CDC7 (0.54) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL28645562 | 0.77 | CDC7 (0.54) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL17340778 | 0.77 | CDC7 (0.54) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL16682680 | 0.71 | CDC7 (0.51) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL30229272 | 0.71 | CDC7 (0.48) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL21247869 | 0.70 | CDC7 (0.47) | CDC7ALDH1A1GAA | |
| SCHEMBL30229287 | 0.70 | CDC7 (0.47) | CDC7ALDH1A1GAAPIM1PIM2 | |
| SCHEMBL9938009 | 0.69 | CDC7 (0.46) | CDC7PIM1PIM2GRM5 | |
| SCHEMBL23541838 | 0.69 | CDC7 (0.55) | CDC7ALDH1A1GAAPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429410-B | Polyheterocyclic substituted pyrimidine or pyridylamine derivatives, compositions and medical uses thereof | 上海海雁医药科技有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-113429410-A | Polyheterocyclic substituted pyrimidine or pyridylamine derivatives, compositions and medical uses thereof | 上海海雁医药科技有限公司 | 2021-09-24 | — | — | CN | disclosed |