Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TNKS | O95271 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160749 | 1.00 | KDM4E (0.59) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL14867343 | 0.90 | HPGD (0.57) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL14867268 | 0.84 | KDM4E (0.48) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL14867282 | 0.84 | KDM4E (0.48) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL14867302 | 0.82 | TNKS (0.53) | TNKS | |
| SCHEMBL28924699 | 0.82 | TNKS (0.65) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL30161077 | 0.82 | TNKS (0.65) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL4769828 | 0.82 | KDM4E (0.63) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL16625064 | 0.82 | TNKS (0.48) | KDM4EHPGDRAB9ANPC1LMNA | |
| SCHEMBL828493 | 0.81 | TNKS (0.63) | KDM4EHPGDRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521310-A | Synthesis method of isoindole isoquinoline spironaphthone compound | 河南师范大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-110041257-B | Method for synthesizing indene spiro indene [1,2-c ] isoquinoline triketone compound | 河南师范大学 | 2021-08-03 | — | — | CN | disclosed |