Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744225 | 0.85 | NPC1 (0.46) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL3362986 | 0.83 | ESR1 (0.49) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL2233660 | 0.82 | HPGD (0.48) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL22756377 | 0.82 | NPC1 (0.44) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL585832 | 0.80 | HPGD (0.47) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL1685076 | 0.78 | HPGD (0.46) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL28570713 | 0.78 | HPGD (0.46) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL14297428 | 0.78 | HPGD (0.46) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL32665936 | 0.78 | HPGD (0.46) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL4936037 | 0.77 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107867987-B | Preparation method of alpha, alpha-dibromo ketone | 复旦大学 | 2021-07-02 | — | — | CN | disclosed |