Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21081514 | 1.00 | PTGER4 (0.49) | PTGER4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL18758576 | 0.94 | PTGER4 (0.43) | PTGER4ALDH1A1LMNAACACB | |
| SCHEMBL28622506 | 0.94 | PTGER4 (0.43) | PTGER4ALDH1A1LMNAACACB | |
| SCHEMBL18758489 | 0.93 | PTGER4 (0.43) | PTGER4ACACB | |
| SCHEMBL28627341 | 0.93 | PTGER4 (0.49) | PTGER4 | |
| SCHEMBL18758530 | 0.93 | PTGER4 (0.46) | PTGER4ACACB | |
| SCHEMBL18758745 | 0.93 | PTGER4 (0.49) | PTGER4 | |
| SCHEMBL18758565 | 0.93 | PTGER4 (0.43) | PTGER4ACACB | |
| SCHEMBL28922420 | 0.93 | PTGER4 (0.43) | PTGER4ACACB | |
| SCHEMBL18758490 | 0.93 | PTGER4 (0.43) | PTGER4ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473497-B | EP4 antagonists | 卫材R&D 管理有限公司 | 2021-09-10 | — | — | CN | disclosed |