Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.71 |
| ▸ | BRD2 | P25440 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | TSPO | P30536 | 1/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.55 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.55 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21904895 | 0.85 | BRD4 (0.72) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL21905014 | 0.83 | BRD4 (1.00) | BRD4 | |
| SCHEMBL21904860 | 0.82 | BRD4 (1.00) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL29848993 | 0.82 | BRD4 (0.77) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL16651923 | 0.82 | BRD4 (0.77) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL16658037 | 0.82 | BRD4 (0.79) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL19930712 | 0.81 | BRD4 (0.68) | BRD4 | |
| SCHEMBL21904853 | 0.79 | BRD4 (1.00) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL21904986 | 0.79 | BRD4 (1.00) | BRD4 | |
| SCHEMBL21904881 | 0.78 | BRD4 (1.00) | BRD4BRD2ADORA2BTSPOEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226322-A | Heterocyclic compounds as BET inhibitors | 诺维逊生物股份有限公司 | 2021-08-06 | — | — | CN | disclosed |