Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133048 | 0.86 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27797476 | 0.83 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL18265606 | 0.83 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27892227 | 0.81 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27509922 | 0.81 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11531013 | 0.81 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1133052 | 0.81 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28486495 | 0.81 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4928448 | 0.80 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL383961 | 0.80 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113347950-A | Ophthalmic lenses, pharmaceutical compositions and uses thereof | 红婴生物科技股份有限公司 | 2021-09-03 | — | — | CN | disclosed |