Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624230 | 0.86 | HDAC1 (0.60) | HDAC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28630210 | 0.83 | HDAC1 (0.57) | HDAC1AKT1AKT2KDM4ERAB9A | |
| SCHEMBL28630911 | 0.83 | NPC1 (0.60) | HDAC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28630208 | 0.81 | NPC1 (0.61) | HDAC1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3547740 | 0.78 | HDAC1 (0.68) | HDAC1AKT1AKT2 | |
| SCHEMBL3550230 | 0.74 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL28615473 | 0.74 | NPC1 (0.60) | HDAC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28616235 | 0.73 | KDM4E (0.58) | HDAC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28620514 | 0.73 | NPC1 (0.59) | HDAC1KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13407635 | 0.73 | HDAC1 (0.49) | HDAC1AKT2KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372346-B | Synthetic method of 3-fatty amine methyl imidazo [1, 2-alpha ] pyridine compound | 南华大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-113372346-A | Synthetic method of 3-fatty amine methyl imidazo [1, 2-alpha ] pyridine compound | 南华大学 | 2021-09-10 | — | — | CN | disclosed |