Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 19/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2863151 | 1.00 | KCNA3 (0.72) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL5353627 | 0.89 | KCNA3 (0.75) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL5353631 | 0.89 | KCNA3 (0.75) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2863226 | 0.88 | KCNA3 (0.74) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2863228 | 0.88 | KCNA3 (0.74) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2860966 | 0.87 | KCNA3 (0.77) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2860963 | 0.87 | KCNA3 (0.77) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL13066423 | 0.85 | KCNA3 (0.80) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL14491271 | 0.84 | KCNA3 (0.72) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3898156 | 0.84 | KCNA3 (1.00) | KCNA3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253328-A1 | Cycloalkyl inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2010-11-24 | — | — | EP | disclosed |
| US-7202253-B2 | Cycloalkyl inhibitors of potassium channel function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-10 | — | — | US | disclosed |