Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.61 |
| ▸ | MC3R | P41968 | 7/20 | 0.61 |
| ▸ | MC5R | P33032 | 6/20 | 0.61 |
| ▸ | MC1R | Q01726 | 5/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20994306 | 0.88 | MC4R (0.59) | MC4RMC3RMC5RMC1RKCNH2 | |
| SCHEMBL28646063 | 0.88 | MC4R (0.63) | MC4RMC3RMC5RMC1RKCNH2 | |
| SCHEMBL20994277 | 0.85 | MC4R (0.55) | MC4RMC3RMC5RMC1RKCNH2 | |
| SCHEMBL21124421 | 0.85 | MC4R (0.58) | MC4RMC3RMC5RMC1RKCNH2 | |
| SCHEMBL21124106 | 0.84 | MC4R (0.55) | MC4RMC3RMC5RMC1RKCNH2 | |
| Hydrochloric Acid SCHEMBL20994311 | 0.84 | MC4R (0.58) | MC4RMC3RMC5RMC1RKCNH2 | |
| Hydrochloric Acid SCHEMBL20994239 | 0.83 | MC4R (0.54) | MC4RMC3RMC5RMC1RKCNH2 | |
| Hydrochloric Acid SCHEMBL20994242 | 0.83 | MC4R (0.54) | MC4RMC3RMC5RMC1RKCNH2 | |
| SCHEMBL15252713 | 0.83 | MC4R (0.64) | MC4RMC3RMC5RMC1RKCNH2 | |
| SCHEMBL1920391 | 0.83 | MC4R (0.64) | MC4RMC3RMC5RMC1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563074-B | Piperazine derivatives | 安斯泰来制药株式会社 | 2021-09-28 | — | — | CN | disclosed |