Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142312 | 0.88 | HDAC1 (0.70) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| SCHEMBL3142296 | 0.88 | HDAC1 (0.70) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| SCHEMBL296512 | 0.86 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| SCHEMBL296513 | 0.86 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| SCHEMBL296996 | 0.86 | HDAC1 (0.73) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| SCHEMBL296995 | 0.86 | HDAC1 (0.73) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| SCHEMBL4507827 | 0.86 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| SCHEMBL4507829 | 0.86 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| Resminostat SCHEMBL299941 | 0.85 | HDAC1 (0.85) | HDAC1HDAC6HDAC3HDAC8HDAC4 | |
| Resminostat SCHEMBL299943 | 0.85 | HDAC1 (0.85) | HDAC1HDAC6HDAC3HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659765-B | Use of dianhydrogalactitol and analogs or derivatives thereof for treating non-small cell lung cancer and ovarian cancer | 德玛医药 | 2021-08-13 | — | — | CN | disclosed |