Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28354909 | 0.82 | EPHX1 (0.70) | EPHX1MDM2CYP1A2CYP2C9TSHR | |
| Potassium Ion SCHEMBL28555977 | 0.81 | MDM2 (0.39) | EPHX1MDM2F13A1TGM2SLC9A1 | |
| SCHEMBL28633045 | 0.80 | EPHX1 (0.47) | EPHX1CYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL28637835 | 0.79 | EPHX1 (0.45) | EPHX1TSHRPARP1 | |
| SCHEMBL28653440 | 0.79 | HDAC4 (0.46) | EPHX1TSHRMEN1KMT2APARP1 | |
| SCHEMBL9692314 | 0.79 | TSHR (0.45) | MDM2F13A1TGM2SLC9A1GAA | |
| SCHEMBL7777512 | 0.79 | TSHR (0.46) | EPHX1MDM2GAATSHRMEN1 | |
| SCHEMBL6069547 | 0.78 | EPHX1 (0.48) | EPHX1CYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL9264620 | 0.78 | EPHX1 (0.48) | EPHX1CYP1A2CYP2C9TSHRMEN1 | |
| SCHEMBL6070434 | 0.78 | EPHX1 (0.48) | EPHX1CYP1A2CYP2C9TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107892666-B | 5-phenylpyrrole derivative and preparation method and application thereof | 吉林医药学院 | 2021-10-15 | — | — | CN | disclosed |