Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | ACR | P10323 | 1/20 | 0.53 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622771 | 0.98 | PARP10 (0.72) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL27867349 | 0.96 | PARP10 (0.70) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL28630979 | 0.96 | PARP10 (0.70) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL28632799 | 0.96 | PARP10 (0.70) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL9360155 | 0.96 | PARP10 (0.70) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL23202513 | 0.92 | PARP10 (0.66) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL9696360 | 0.92 | PARP10 (0.66) | PARP10KMT2AMEN1MAPTTDP1 | |
| Terephthalic Acid SCHEMBL28437942 | 0.92 | PARP10 (0.63) | PARP10KMT2AMEN1MAPTTDP1 | |
| Benzoic Acid SCHEMBL28346471 | 0.92 | PARP10 (0.63) | PARP10KMT2AMEN1MAPTTDP1 | |
| SCHEMBL817796 | 0.92 | PARP10 (0.63) | PARP10KMT2AMEN1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214223-B | Preparation method of Voranolan fumarate impurity | 南京海纳医药科技股份有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-113214223-A | Preparation method of Voranolan fumarate impurity | 南京海纳医药科技股份有限公司 | 2021-08-06 | — | — | CN | disclosed |