SCHEMBL28634616

SCHEMBL28634616

Cc1cnnc(C(N)=O)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT3 Q9NTG7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NNMT P40261 4/20 0.33
LCK P06239 2/20 0.33
BTK Q06187 2/20 0.33
IKBKB O14920 2/20 0.33
ADORA2A P29274 2/20 0.33
ADORA1 P30542 2/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
PKM P14618 1/20 0.33
ADORA2B P29275 1/20 0.33
KAT2B Q92831 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
PDPK1 O15530 1/20 0.32
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31288009 1.00 SIRT3 (0.37) SIRT3TDP1NNMTLCKBTK
SCHEMBL31211618 0.77 SIRT3 (0.33) SIRT3TDP1NNMTLCKBTK
SCHEMBL31211660 0.76 CCNA2 (0.34) SIRT3TDP1LCKBTKKDM4E
SCHEMBL20555873 0.72 PARP1 (0.39) SIRT3TDP1NNMTIKBKBADORA2A
SCHEMBL29827533 0.72 PARP1 (0.39) SIRT3TDP1NNMTIKBKBADORA2A
SCHEMBL22322612 0.71 POLB (0.40) SIRT3TDP1NNMTKDM4EMEN1
SCHEMBL1403852 0.71 SIRT3 (0.46) SIRT3TDP1NNMTLCKBTK
SCHEMBL31304205 0.70 TYR (0.39) KDM4EKAT2BMEN1KMT2APOLB
SCHEMBL22290164 0.70 KDM4E (0.31) KDM4E
SCHEMBL20203237 0.69 POLB (0.39) SIRT3TDP1NNMTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113329629-A Herbicidal compounds 先正达农作物保护股份公司 2021-08-31 CN disclosed