Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448068 | 1.00 | MAPK1 (0.59) | MAPK1MEN1KMT2ATSHRAURKA | |
| SCHEMBL17382717 | 0.84 | MAPT (0.53) | MAPK1MEN1KMT2ATSHRMAPT | |
| SCHEMBL28236209 | 0.84 | MAPT (0.47) | MAPK1MEN1KMT2ATSHRMAPT | |
| SCHEMBL11175497 | 0.83 | GAA (0.49) | MAPK1MEN1KMT2ATSHRAURKA | |
| SCHEMBL30902223 | 0.82 | TDP1 (0.61) | MAPK1MEN1KMT2ATSHRAURKA | |
| SCHEMBL3279472 | 0.82 | TDP1 (0.61) | MAPK1MEN1KMT2ATSHRAURKA | |
| SCHEMBL11125372 | 0.79 | MAPT (0.51) | MAPK1MEN1KMT2ATSHRAURKA | |
| SCHEMBL1300022 | 0.79 | MAPT (0.64) | MAPK1MEN1KMT2ATSHRMAPT | |
| SCHEMBL15380326 | 0.79 | MAPT (0.46) | MAPK1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL15379850 | 0.79 | TDP1 (0.48) | MAPK1MEN1KMT2AAURKAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |