⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30918471 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL126755 | 0.98 | CCR1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL28024971 | 0.98 | CCR1 (0.46) | — | |
| Cyanide SCHEMBL28127694 | 0.94 | CCR1 (0.43) | — | |
| SCHEMBL18682734 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL14573460 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL469189 | 0.78 | — | — | |
| SCHEMBL21166 | 0.76 | — | — | |
| SCHEMBL9645202 | 0.76 | — | — | |
| SCHEMBL1515370 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398139-B2 | Modulators of AMPA receptor signaling | CENTRE FOR ADDICTION AND MENTAL HEALTH (CA) | 2025-08-26 | — | — | US | disclosed |
| EP-3935059-B1 | MODULATORS OF AMPA RECEPTOR SIGNALING | CAMH (CA) | 2025-04-23 | — | — | EP | disclosed |
| US-20250034143-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, LLC (US) | 2025-01-30 | — | — | US | disclosed |
| US-12144816-B2 | Substituted indole Mcl-1 inhibitors | VANDERBILT UNIVERSITY (US) | 2024-11-19 | — | — | US | disclosed |
| CN-117720518-B | Benzimidazole compound, preparation method thereof, pharmaceutical composition and application | 江苏海洋大学 | 2024-08-13 | — | — | CN | disclosed |
| US-20240231228-A1 | RESIST COMPOSITION AND METHOD OF FORMING PATTERN BY USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2024-07-11 | — | — | US | disclosed |
| US-20240228463-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | GENENTECH, INC. (US) | 2024-07-11 | — | — | US | disclosed |
| US-11999716-B2 | WDR5 inhibitors and modulators | VANDERBILT UNIVERSITY (US) | 2024-06-04 | — | — | US | disclosed |
| US-11958854-B2 | Substituted xanthines and methods of use thereof | HYDRA BIOSCIENCES, LLC (US) | 2024-04-16 | — | — | US | disclosed |
| CN-117720518-A | Benzimidazole compound, preparation method thereof, pharmaceutical composition and application | 江苏海洋大学 | 2024-03-19 | — | — | CN | disclosed |
| US-4511720-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0127763-A1 | Tricyclic ethers, process for their preparation, their use and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-12-12 | — | — | EP | disclosed |
| US-4355033-A | TREATMENT OF HYPERTENSION | HOFFMAN-LA ROCHE INC. (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0002010-B1 | DERIVATIVES OF 2-IMINO-IMIDAZOLIDINE, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-07-14 | — | — | EP | disclosed |
| EP-0001279-B1 | IMIDAZOLE DERIVATIVES THEIR SYNTHESIS AND THEIR PHARMACEUTICAL FORMULATIONS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-09-30 | — | — | EP | disclosed |
| US-4248880-A | IMIDAZOLE OR THIAZOLE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-03 | — | — | US | disclosed |
| US-4244957-A | HYPOTENSIVE AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4182766-A | ANTIULCER AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-01-08 | — | — | US | disclosed |
| EP-0002010-A1 | Derivatives of 2-imino-imidazolidine, processes for their preparation, pharmaceutical compositions containing them and intermediates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-05-30 | — | — | EP | disclosed |
| EP-0001279-A1 | Imidazole derivatives their synthesis and their pharmaceutical formulations | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-04-04 | — | — | EP | disclosed |