Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796546 | 0.82 | HTR2B (0.68) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL5820630 | 0.81 | HTR2B (0.57) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL5613233 | 0.81 | HTR2B (0.66) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL7771113 | 0.79 | HTR2B (0.59) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL10911535 | 0.78 | HTR2B (0.62) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL17183668 | 0.77 | HTR2B (0.61) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL31229252 | 0.76 | HSP90AA1 (0.67) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL67699 | 0.76 | HSP90AA1 (0.67) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL1567078 | 0.76 | HTR2B (0.60) | HTR2BHTR7PNMTNPC1RAB9A | |
| SCHEMBL29638295 | 0.76 | HSP90AA1 (0.67) | HTR2BHTR7PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423435-A | Treatment of respiratory disorders using arachidonic acid 15-lipoxygenase (ALOX15) inhibitors | 雷杰纳荣制药公司 | 2021-09-21 | — | — | CN | disclosed |