Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26695363 | 0.87 | FUCA1 (0.50) | CHRM2CHRM4CHRM5FUCA1MAPT | |
| SCHEMBL27969697 | 0.81 | MAPT (0.51) | CHRM2CHRM4CHRM5FUCA1MAPT | |
| SCHEMBL28868216 | 0.79 | CHRM2 (0.44) | CHRM2CHRM4CHRM5FUCA1MAPT | |
| SCHEMBL12830800 | 0.77 | CHRM2 (0.59) | CHRM2CHRM4CHRM5FUCA1MAPT | |
| SCHEMBL16766562 | 0.76 | CHRM2 (0.62) | CHRM2CHRM4CHRM5MAPTMEN1 | |
| SCHEMBL16766586 | 0.76 | CHRM2 (0.62) | CHRM2CHRM4CHRM5MAPTMEN1 | |
| SCHEMBL694189 | 0.76 | CHRM2 (0.62) | CHRM2CHRM4CHRM5MAPTMEN1 | |
| SCHEMBL9167840 | 0.76 | CHRM2 (0.62) | CHRM2CHRM4CHRM5FUCA1MAPT | |
| SCHEMBL693619 | 0.76 | CHRM2 (0.53) | CHRM2CHRM4CHRM5FUCA1MAPT | |
| SCHEMBL13993541 | 0.76 | CHRM2 (0.62) | CHRM2CHRM4CHRM5MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603683-A | Substituted phenyl oxazolidinones for antimicrobial therapy | 结核病药物开发全球联盟公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-108348507-B | Substituted phenyl oxazolidinones for antimicrobial therapy | 结核病药物开发全球联盟公司 | 2021-10-08 | — | — | CN | disclosed |