Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458909 | 0.98 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL21876995 | 0.98 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL20046242 | 0.95 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL24480809 | 0.93 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL26090937 | 0.93 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL21069737 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL22609548 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL14497257 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL31085811 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL29260056 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527260-A | Compound capable of degrading STAT3 enzyme, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-10-22 | — | — | CN | disclosed |