SCHEMBL28636366

SCHEMBL28636366

COc1ccc(C(OCC2OC(n3cc(C=CC(=O)NCCCCCCNC(=O)C(F)(F)F)c(=O)[nH]c3=O)CC2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414478 1.00 TYMS (0.30) TYMS
SCHEMBL13403288 0.96 TYMS (0.30) TYMS
SCHEMBL8165596 0.91 TYMS (0.31) TYMS
SCHEMBL8166011 0.89 TYMS (0.32) TYMS
SCHEMBL19970915 0.88
SCHEMBL18133272 0.88 TYMP (0.33) TYMS
SCHEMBL12259020 0.88 CA4 (0.30)
SCHEMBL13610655 0.88 CA4 (0.30)
SCHEMBL12259024 0.87
SCHEMBL13610670 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108070009-B Method for preparing DNA coding compound library and initial fragment compound and prepared DNA coding compound 上海药明康德新药开发有限公司 2021-04-13 CN disclosed