Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.62 |
| ▸ | BCL2 | P10415 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833832 | 0.85 | KMT2A (0.62) | HDAC1HDAC6HDAC3HDAC7HDAC2 | |
| SCHEMBL17992529 | 0.81 | BRD4 (0.71) | KMT2AMAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL29437237 | 0.81 | BRD4 (0.71) | KMT2AMAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL31373066 | 0.81 | MEN1 (0.64) | HDAC1HDAC6HDAC3HDAC7HDAC2 | |
| SCHEMBL29437260 | 0.80 | BRD4 (0.72) | KMT2AMAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL29437268 | 0.80 | BRD4 (0.72) | KMT2AMAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL17992487 | 0.80 | BRD4 (0.72) | KMT2AMAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL17992485 | 0.80 | BRD4 (0.72) | KMT2AMAPTHTTNPSR1L3MBTL1 | |
| SCHEMBL3404873 | 0.80 | KMT2A (0.67) | MEN1KMT2AUSP2MAPTHTT | |
| SCHEMBL17992519 | 0.78 | BRD4 (0.61) | KMT2AMAPTHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107540608-B | 4-substituted naphthalimide compound and application thereof | 大连理工大学 | 2021-10-19 | — | — | CN | disclosed |