SCHEMBL2863752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2858272	0.96	KDM4E (0.47)	KDM4EPPARAMAPTTSHRPDE4B
	SCHEMBL2859122	0.93	KDM4E (0.52)	KDM4EPPARAMAPTTSHRMEN1
	SCHEMBL2869164	0.92	KDM4E (0.55)	KDM4ETSHRMEN1KMT2APDE4B
	SCHEMBL2861258	0.92	KDM4E (0.51)	KDM4EPPARAMAPTTSHRMEN1
	SCHEMBL2861769	0.89	KDM4E (0.47)	KDM4EPPARAMAPTTSHRPDE4B
	SCHEMBL2858164	0.89	KDM4E (0.46)	KDM4EPPARAMAPTTSHRMEN1
	SCHEMBL2859385	0.88	KDM4E (0.46)	KDM4ETSHRPDE4BCYP1A2CYP3A4
	SCHEMBL2860147	0.87	KDM4E (0.48)	KDM4ETSHRMEN1KMT2APDE4B
	SCHEMBL2858197	0.87	KDM4E (0.46)	KDM4EMAPTTSHRPDE4BALDH1A1
	SCHEMBL2866304	0.86	KDM4E (0.47)	KDM4EMAPTTSHRPDE4BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.