Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 18/20 | 0.61 |
| ▸ | VEGFA | P15692 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18688710 | 0.85 | EPAS1 (0.58) | EPAS1VEGFA | |
| SCHEMBL19870952 | 0.84 | EPAS1 (0.59) | EPAS1VEGFA | |
| SCHEMBL18688694 | 0.83 | EPAS1 (0.56) | EPAS1VEGFA | |
| SCHEMBL19870924 | 0.83 | EPAS1 (0.56) | EPAS1VEGFA | |
| SCHEMBL19870919 | 0.83 | EPAS1 (0.56) | EPAS1VEGFA | |
| SCHEMBL19870949 | 0.82 | EPAS1 (0.55) | EPAS1VEGFA | |
| SCHEMBL19870907 | 0.82 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL19870928 | 0.82 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL21362794 | 0.82 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL20259903 | 0.82 | EPAS1 (0.57) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372550-B | Aryl ethers and their use | 佩洛通治疗公司 | 2021-08-24 | — | — | CN | disclosed |