Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 20/20 | 0.57 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | PMAIP1 | Q13794 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637645 | 0.94 | MCL1 (0.57) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28648137 | 0.94 | MCL1 (0.56) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28643140 | 0.94 | MCL1 (0.51) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL19634883 | 0.94 | MCL1 (0.51) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28656424 | 0.93 | MCL1 (0.54) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28656449 | 0.93 | MCL1 (0.54) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28637897 | 0.93 | MCL1 (0.55) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28643114 | 0.93 | MCL1 (0.51) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28647215 | 0.92 | MCL1 (0.61) | MCL1BCL2ALBPMAIP1 | |
| SCHEMBL28926855 | 0.91 | MCL1 (0.59) | MCL1BCL2ALBPMAIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715632-B | Macrocyclic indole derivatives | 拜尔公开股份有限公司 | 2021-10-26 | — | — | CN | disclosed |