Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642231 | 1.00 | GAA (0.53) | GAAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28655996 | 0.98 | MEN1 (0.53) | GAAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28633426 | 0.87 | PPARA (0.56) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL14158969 | 0.84 | MEN1 (0.50) | GAAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28651868 | 0.84 | MEN1 (0.50) | GAAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13568875 | 0.84 | MEN1 (0.61) | GAAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10593412 | 0.82 | MEN1 (0.62) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL13450152 | 0.82 | MEN1 (0.51) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL20225816 | 0.82 | KDM4E (0.62) | MEN1KMT2AHDAC1HDAC2KDM4E | |
| SCHEMBL20225817 | 0.82 | KDM4E (0.62) | MEN1KMT2AHDAC1HDAC2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480418-B | Compound and application thereof in preparing medicine for treating cancer | 上海健康医学院 | 2022-09-06 | — | — | CN | disclosed |
| CN-113480418-A | New compound and application thereof in preparing medicine for treating cancer | 上海健康医学院 | 2021-10-08 | — | — | CN | disclosed |