Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL986789 | 1.00 | KMT2A (0.40) | KMT2AMAPTGAAMEN1FFAR3 | |
| SCHEMBL85990 | 0.91 | GAA (0.38) | KMT2AMAPTGAAMEN1ALDH1A1 | |
| Acetic Acid SCHEMBL2854448 | 0.90 | KMT2A (0.36) | KMT2AMAPTGAAMEN1ALDH1A1 | |
| Acetic Acid SCHEMBL14237282 | 0.89 | SMN1; SMN2 (0.37) | KMT2AMAPTGAAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7516042 | 0.88 | GAA (0.37) | KMT2AMAPTGAAMEN1ALDH1A1 | |
| Ethylene SCHEMBL3939551 | 0.86 | GAA (0.36) | KMT2AMAPTGAAMEN1ALDH1A1 | |
| Acetic Acid SCHEMBL984620 | 0.82 | TSHR (0.39) | KMT2AGAAMEN1FFAR3LCK | |
| Nitrilotriacetic Acid SCHEMBL15163060 | 0.81 | TDP1 (0.35) | KMT2AMAPTGAAMEN1ALDH1A1 | |
| SCHEMBL2863909 | 0.81 | GAA (0.49) | KMT2AMAPTGAAMEN1ALDH1A1 | |
| Nitrilotriacetic Acid SCHEMBL984675 | 0.81 | TDP1 (0.35) | KMT2AMAPTGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499286-B1 | STABILIZED BODY CARE PRODUCTS AND HOUSEHOLD PRODUCTS | BASF SE (DE) | 2010-04-07 | — | — | EP | claimed |
| EP-1680541-A2 | STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS | Ciba SC Holding AG (CH) | 2006-07-19 | — | — | EP | claimed |
| WO-2005042828-A2 | STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-05-12 | — | — | WO | claimed |