Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000669 | 0.89 | KDM4E (0.80) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL1509430 | 0.83 | KDM4E (0.71) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL1509510 | 0.83 | KDM4E (0.71) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL1509424 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL7517869 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL30112815 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1MAPTHTTIKBKB | |
| Hydrochloric Acid SCHEMBL8565531 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL29946624 | 0.79 | IKBKB (0.78) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL29946540 | 0.78 | IKBKB (0.77) | KDM4EALDH1A1MAPTHTTIKBKB | |
| SCHEMBL28922380 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1MAPTHTTIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354630-B | 5,6-dihydrobenzo [ h ] quinazoline compound and application thereof | 江南大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-113354630-A | 5, 6-dihydrobenzo [ h ] quinazoline compound and application thereof | 江南大学 | 2021-09-07 | — | — | CN | disclosed |