Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.72 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.72 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.72 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28739999 | 0.82 | FGFR4 (0.59) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL16071435 | 0.80 | FGFR4 (0.77) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28633170 | 0.77 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28651460 | 0.76 | FGFR4 (0.63) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24690536 | 0.75 | FGFR4 (0.59) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL19069136 | 0.75 | FGFR4 (0.81) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16133989 | 0.74 | FGFR4 (0.80) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071774 | 0.74 | FGFR4 (0.80) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071620 | 0.74 | FGFR4 (0.80) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24690535 | 0.73 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527311-B | FGFR4 inhibitor, composition and application thereof in preparation of medicines | 中南大学湘雅医院 | 2022-05-06 | — | — | CN | disclosed |
| CN-113527311-A | FGFR4 inhibitor, composition and application thereof in preparation of medicines | 中南大学湘雅医院 | 2021-10-22 | — | — | CN | disclosed |