Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28100077 | 0.95 | TSHR (0.55) | PARP10PARP15TSHRTP53PARP1 | |
| Benzene SCHEMBL28239358 | 0.92 | MAPT (0.54) | PARP10PARP15TSHRPARP1CYP2C19 | |
| SCHEMBL174536 | 0.92 | PARP10 (0.46) | PARP10PARP15TSHRPARP1CYP2C19 | |
| Oxalic Acid SCHEMBL27509979 | 0.90 | PARP1 (0.46) | PARP10PARP15TSHRPARP1CYP2C19 | |
| SCHEMBL28344986 | 0.90 | PARP10 (0.45) | PARP10PARP15TSHRPARP1CYP2C19 | |
| Hydrochloric Acid SCHEMBL27677598 | 0.90 | PARP10 (0.45) | PARP10PARP15TSHRPARP1CYP2C19 | |
| Hydrazine SCHEMBL28084706 | 0.90 | PARP10 (0.45) | PARP10PARP15TSHRPARP1CYP2C19 | |
| Urea SCHEMBL11673195 | 0.90 | PARP10 (0.45) | PARP10PARP15TSHRPARP1CYP2C19 | |
| Water SCHEMBL27561730 | 0.90 | PARP10 (0.45) | PARP10PARP15TSHRPARP1CYP2C19 | |
| SCHEMBL28704898 | 0.88 | PARP10 (0.46) | PARP10PARP15TSHRPARP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114725341-A | Positive electrode active material, electrochemical device, and electronic device | 宁德时代新能源科技股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114709368-A | Negative pole piece of sodium ion battery, electrochemical device and electronic equipment | 宁德时代新能源科技股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114613954-A | Positive electrode active material, electrochemical device, and electronic device | 宁德时代新能源科技股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-113437276-B | Positive electrode active material, electrochemical device, and electronic device | 宁德时代新能源科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-113437254-B | Negative pole piece of sodium ion battery, electrochemical device and electronic equipment | 宁德时代新能源科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-113437275-B | Positive electrode active material, electrochemical device, and electronic device | 宁德时代新能源科技股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-113437254-A | Negative pole piece of sodium ion battery, electrochemical device and electronic equipment | 宁德时代新能源科技股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-113437276-A | Positive electrode active material, electrochemical device, and electronic device | 宁德时代新能源科技股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-113437275-A | Positive electrode active material, electrochemical device, and electronic device | 宁德时代新能源科技股份有限公司 | 2021-09-24 | — | — | CN | disclosed |