Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.56 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28138635 | 0.89 | GPBAR1 (0.56) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL28642624 | 0.89 | GPBAR1 (0.56) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL28696373 | 0.88 | GPBAR1 (0.55) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL28646758 | 0.86 | GPBAR1 (0.62) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL5154459 | 0.86 | GPBAR1 (0.62) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL5667894 | 0.86 | GPBAR1 (0.62) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL28138634 | 0.86 | GPBAR1 (0.62) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL3130080 | 0.85 | GPBAR1 (0.58) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| SCHEMBL28703638 | 0.84 | GPBAR1 (0.61) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 | |
| Glycine SCHEMBL28353212 | 0.82 | GPBAR1 (0.61) | GPBAR1EPHA2LMNAAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133421-B | Preparation method of beta-mouse cholic acid | 中山百灵生物技术股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-113336818-B | Preparation method of alpha-murine cholic acid | 中山百灵生物技术股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-114133421-A | Preparation method of beta-mouse cholic acid | 中山百灵生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-113336818-A | Preparation method of alpha-murine cholic acid | 中山百灵生物技术股份有限公司 | 2021-09-03 | — | — | CN | disclosed |