Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PER2 | O15055 | 7/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146924 | 0.82 | — | — | |
| SCHEMBL6715928 | 0.82 | — | — | |
| SCHEMBL14749922 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL27550542 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL17205497 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL27818746 | 0.80 | PIK3CD (0.45) | PIK3CDPER2CHRM2CHRM4CHRM5 | |
| Methylene Chloride SCHEMBL28327699 | 0.79 | PIK3CD (0.46) | PIK3CDPER2CHRM2CHRM4CHRM5 | |
| Formic Acid SCHEMBL31706436 | 0.77 | PIK3CD (0.40) | PIK3CDPER2CHRM2CHRM4CHRM5 | |
| SCHEMBL27704456 | 0.75 | PIK3CD (0.41) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5053896 | 0.73 | PIK3CD (0.44) | PIK3CDPER2CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108369358-B | Composition for producing liquid crystal alignment film, liquid crystal alignment film using same, method for producing same, liquid crystal display element having liquid crystal alignment film, and method for producing same | 日产化学工业株式会社 | 2022-02-25 | — | — | CN | disclosed |
| CN-109416485-B | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and novel monomer | 日产化学株式会社 | 2021-11-02 | — | — | CN | disclosed |
| CN-107849330-B | Polymer composition, liquid crystal aligning agent, liquid crystal alignment film, substrate having liquid crystal alignment film, and liquid crystal display element having liquid crystal alignment film | 日产化学工业株式会社 | 2021-11-02 | — | — | CN | disclosed |
| CN-110072946-B | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element | 日产化学株式会社 | 2021-10-15 | — | — | CN | disclosed |
| CN-107924088-B | Polymer composition, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element | 日产化学工业株式会社 | 2021-10-12 | — | — | CN | disclosed |
| CN-113444376-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element | 日产化学工业株式会社 | 2021-09-28 | — | — | CN | disclosed |