Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29140486 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL29140479 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL29140484 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL28634396 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL28628532 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL23088976 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL28798486 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL28925092 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL29140480 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL29140478 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480427-B | Method for producing low-chroma high-concentration lactic acid by comprehensively utilizing straws | 上海汉禾生物新材料科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113480427-A | Method for producing low-chroma high-concentration lactic acid by comprehensively utilizing straws | 上海汉禾生物新材料科技有限公司 | 2021-10-08 | — | — | CN | disclosed |