Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 3/20 | 0.60 |
| ▸ | BTK | Q06187 | 8/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633843 | 1.00 | TNK2 (0.60) | TNK2BTKFGFR4FGFR1FGFR3 | |
| SCHEMBL26820282 | 0.95 | TNK2 (0.59) | TNK2BTKFGFR4FGFR1FGFR3 | |
| SCHEMBL26791421 | 0.95 | TNK2 (0.59) | TNK2BTKFGFR4FGFR1FGFR3 | |
| SCHEMBL28652429 | 0.89 | TNK2 (0.51) | TNK2BTKHPGDSJAK2JAK1 | |
| SCHEMBL18345263 | 0.89 | TNK2 (0.60) | TNK2BTKFGFR4FGFR1FGFR3 | |
| SCHEMBL16748869 | 0.89 | TNK2 (0.60) | TNK2BTKFGFR4FGFR1FGFR3 | |
| SCHEMBL26791423 | 0.83 | TNK2 (0.50) | TNK2BTKFGFR4FGFR1FGFR3 | |
| SCHEMBL21159579 | 0.81 | TNK2 (0.51) | TNK2BTKHPGDSJAK2JAK1 | |
| SCHEMBL21138763 | 0.81 | TNK2 (0.51) | TNK2BTKHPGDSJAK2JAK1 | |
| SCHEMBL29926503 | 0.81 | TNK2 (0.51) | TNK2BTKHPGDSJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493439-B | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113493439-A | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-10-12 | — | — | CN | disclosed |