Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644185 | 1.00 | GNRHR (0.35) | GNRHRCYP3A4DHODHMALT1UTS2R | |
| SCHEMBL19873904 | 0.92 | GNRHR (0.36) | GNRHRCYP3A4DHODHMALT1UTS2R | |
| SCHEMBL17870696 | 0.92 | GNRHR (0.36) | GNRHRCYP3A4DHODHMALT1UTS2R | |
| SCHEMBL19873888 | 0.88 | GNRHR (0.34) | GNRHRCYP3A4DHODHMALT1UTS2R | |
| SCHEMBL30178450 | 0.88 | GNRHR (0.34) | GNRHRCYP3A4DHODHMALT1UTS2R | |
| SCHEMBL19873887 | 0.88 | GNRHR (0.34) | GNRHRCYP3A4DHODHMALT1UTS2R | |
| SCHEMBL28644101 | 0.84 | GNRHR (0.40) | GNRHRCYP3A4P2RX3SMN1; SMN2KDM4E | |
| SCHEMBL28641621 | 0.84 | GNRHR (0.39) | GNRHRCYP3A4P2RX3KDM4EALDH1A1 | |
| SCHEMBL28663476 | 0.84 | GNRHR (0.39) | GNRHRCYP3A4P2RX3KDM4EMEN1 | |
| SCHEMBL28663474 | 0.84 | GNRHR (0.39) | GNRHRCYP3A4P2RX3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |