SCHEMBL28645167

SCHEMBL28645167

OCc1c(Cl)cccc1-n1cc(-c2ccccc2)nn1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.69
NOTUM Q6P988 4/20 0.52
ABCB1 P08183 1/20 0.47
ABCG2 Q9UNQ0 1/20 0.47
LDHA P00338 2/20 0.46
CYP19A1 P11511 1/20 0.42
DRD2 P14416 2/20 0.42
DRD3 P35462 2/20 0.42
OGT O15294 1/20 0.41
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.40
TYMS P04818 1/20 0.39
PTGS2 P35354 2/20 0.39
FLT3 P36888 1/20 0.39
GSK3B P49841 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28326485 0.84 BCHE (0.54) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL28046686 0.82 BCHE (1.00) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL28661839 0.81 BCHE (0.65) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL28645409 0.78 BCHE (0.57) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL28326470 0.76 BCHE (0.57) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL28644691 0.75 BCHE (0.56) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL28650367 0.75 BCHE (0.52) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL28327756 0.75 BCHE (0.56) BCHENOTUMABCB1ABCG2LDHA
SCHEMBL16294830 0.73 BCHE (0.61) BCHEABCB1ABCG2LDHACYP19A1
SCHEMBL19412841 0.73 BCHE (0.57) BCHENOTUMABCB1ABCG2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110423239-B 1, 3-oxazine 1,2, 3-triazole derivative and synthetic method and application thereof 昆明理工大学 2021-10-26 CN claimed
CN-110423239-B 1, 3-oxazine 1,2, 3-triazole derivative and synthetic method and application thereof 昆明理工大学 2021-10-26 CN disclosed