Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850138 | 1.00 | NR1H2 (0.47) | NR1H2HPGDDPP4KDM4EPKM | |
| SCHEMBL28647908 | 0.90 | DPP4 (0.49) | NR1H2HPGDDPP4KDM4EPKM | |
| SCHEMBL28643401 | 0.90 | DPP4 (0.49) | NR1H2HPGDDPP4KDM4EPKM | |
| SCHEMBL23850137 | 0.86 | NR1H2 (0.51) | NR1H2HPGDDPP4KDM4EPKM | |
| SCHEMBL2549045 | 0.86 | HPGD (0.48) | NR1H2HPGDDPP4KDM4EPKM | |
| SCHEMBL18497484 | 0.86 | NR1H2 (0.49) | NR1H2HPGDKDM4EPKMGPR119 | |
| SCHEMBL5574074 | 0.85 | HPGD (0.50) | NR1H2HPGDDPP4KDM4EPKM | |
| SCHEMBL20061028 | 0.84 | KDM4E (0.49) | NR1H2HPGDKDM4EPKMGPR119 | |
| SCHEMBL22284308 | 0.83 | NR1H2 (0.47) | NR1H2HPGDDPP4KDM4EPKM | |
| SCHEMBL13715268 | 0.83 | HPGD (0.46) | NR1H2HPGDDPP4KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113573779-A | C10-alkylene substituted 13-membered macrolides and their use | 齐卡尼治疗股份有限公司 | 2021-10-29 | — | — | CN | disclosed |