Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL548048 | 1.00 | TP53 (0.53) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL11600706 | 1.00 | TP53 (0.53) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL28026702 | 1.00 | TP53 (0.53) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL28645502 | 1.00 | TP53 (0.53) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL28027344 | 0.97 | TP53 (0.57) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL26687929 | 0.97 | TP53 (0.57) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL28871047 | 0.97 | TP53 (0.57) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL21834232 | 0.97 | TP53 (0.57) | TP53FFAR3LCKFYNALDH1A1 | |
| Diethylamine SCHEMBL1427970 | 0.97 | — | — | |
| Diethylamine SCHEMBL25331561 | 0.93 | TP53 (0.53) | TP53FFAR3LCKFYNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113528219-A | Environment-friendly water-soluble metal processing cutting fluid | 重庆德蒙特科技发展有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-116765919-A | Use device of environment-friendly water-soluble metal processing cutting fluid | 重庆德蒙特科技发展有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113528219-A | Environment-friendly water-soluble metal processing cutting fluid | 重庆德蒙特科技发展有限公司 | 2021-10-22 | — | — | CN | disclosed |