Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.60 |
| ▸ | ECE1 | P42892 | 2/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | LGMN | Q99538 | 3/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819863 | 1.00 | MME (0.60) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL19384748 | 0.99 | MME (0.59) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL14371944 | 0.99 | MME (0.59) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL20263591 | 0.99 | MME (0.59) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL20677213 | 0.99 | MME (0.59) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL24992811 | 0.99 | MME (0.59) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL21523353 | 0.93 | MME (0.55) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL21523352 | 0.93 | MME (0.55) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL20323161 | 0.93 | MME (0.55) | MMEECE1CTSKPSMB1LGMN | |
| SCHEMBL20287884 | 0.91 | MME (0.52) | MMEECE1CTSKPSMB1LGMN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118871422-A | 3-Alkynyl carboxamides as AEP modulators | 豪夫迈·罗氏有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-117813284-A | Halogenated acethydrazide as AEP inhibitor | 豪夫迈·罗氏有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-11946079-B2 | Method for producing a protein hydrolysate using an endopeptidase and a carboxypeptidase | NOVOZYMES A/S (DK) | 2024-04-02 | — | — | US | disclosed |
| CN-116059390-A | Prodrugs of cytotoxic actives with enzymatically cleavable groups | 拜耳制药股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-114917361-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| US-20220127592-A1 | POLYPEPTIDE, USE AND METHOD FOR HYDROLYSING PROTEIN | NOVOZYMES A/S (DK) | 2022-04-28 | — | — | US | disclosed |
| CN-108884386-B | Chemiluminescent probe for diagnosis and in vivo imaging | 特拉维夫大学拉玛特有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-107635586-B | Antibody-drug conjugates (ADC) of KSP inhibitors with aglycosylated anti-TWEAKR antibodies | 拜耳医药股份有限公司 | 2021-09-24 | — | — | CN | disclosed |