Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044848 | 1.00 | MEN1 (0.39) | MEN1KMT2ANR1H2MAPTALDH1A1 | |
| SCHEMBL21680263 | 0.84 | SMN1; SMN2 (0.42) | NR1H2MAPTALDH1A1ESR2CTSK | |
| SCHEMBL28457997 | 0.83 | SMN1; SMN2 (0.39) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL3806239 | 0.81 | MAPT (0.41) | MEN1KMT2ANR1H2MAPTALDH1A1 | |
| SCHEMBL3806240 | 0.81 | MAPT (0.41) | MEN1KMT2ANR1H2MAPTALDH1A1 | |
| SCHEMBL31465204 | 0.79 | MEN1 (0.49) | MEN1KMT2ANR1H2MAPTALDH1A1 | |
| SCHEMBL3806372 | 0.79 | MEN1 (0.43) | MEN1KMT2ANR1H2MAPTALDH1A1 | |
| SCHEMBL3252604 | 0.79 | MEN1 (0.43) | MEN1KMT2ANR1H2MAPTALDH1A1 | |
| SCHEMBL3252597 | 0.79 | MEN1 (0.43) | MEN1KMT2ANR1H2MAPTALDH1A1 | |
| SCHEMBL13155039 | 0.77 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493439-B | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113493439-A | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-10-12 | — | — | CN | disclosed |