Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL2851390 | 1.00 | CHRNA7 (0.44) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| SCHEMBL2855680 | 0.96 | CHRNA7 (0.47) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| SCHEMBL2851299 | 0.96 | CHRNA7 (0.47) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| SCHEMBL2851300 | 0.96 | CHRNA7 (0.47) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| Formic Acid SCHEMBL2857648 | 0.92 | GSK3B (0.48) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| Formic Acid SCHEMBL2861542 | 0.92 | GSK3B (0.48) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| Formic Acid SCHEMBL2859293 | 0.92 | GSK3B (0.48) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| Formic Acid SCHEMBL2851406 | 0.89 | CHRNA7 (0.42) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| Formic Acid SCHEMBL2858552 | 0.89 | CHRNA7 (0.42) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 | |
| Formic Acid SCHEMBL2857775 | 0.89 | CHRNA7 (0.42) | CHRNA7HTR3AHTR3EHTR3BCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828179-B1 | NICOTINIC ALPHA-7 RECEPTOR LIGANDS AGAINST CNS-RELATED DISEASES | MEMORY PHARM CORP (US) | 2010-01-20 | — | — | EP | claimed |