SCHEMBL28647463

SCHEMBL28647463

CCN=C=NC(CC)CC(CC)(CC)N(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3856957 0.74 CYP1A2 (0.33) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL7284036 0.66 CYP1A2 (0.50) CYP1A2CYP2D6
SCHEMBL2568072 0.63 CYP1A2 (0.38) CYP1A2CYP2D6
SCHEMBL34280 0.63 CYP1A2 (0.38) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL1071947 0.62 CYP1A2 (0.36) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL5078995 0.62 CYP1A2 (0.36) CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL153625 0.62 CYP1A2 (0.36) CYP1A2CYP2D6
SCHEMBL21808585 0.62 CYP1A2 (0.36) CYP1A2CYP2D6
SCHEMBL6443991 0.61 CYP1A2 (0.39) CYP1A2CYP2D6
Iodomethane SCHEMBL898632 0.61 CYP1A2 (0.35) CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112823005-A Pyrrolopyrimidine ITK inhibitors 阿克拉瑞斯治疗股份有限公司 2021-05-18 CN disclosed