Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 19/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491863 | 1.00 | KCNA3 (0.58) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL14491857 | 1.00 | KCNA3 (0.58) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2857520 | 1.00 | KCNA3 (0.58) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2859763 | 0.92 | KCNA3 (0.62) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2864692 | 0.91 | KCNA3 (0.57) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL13067028 | 0.89 | KCNA3 (0.56) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2855033 | 0.89 | KCNA3 (0.56) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL13066395 | 0.89 | KCNA3 (0.56) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL2861845 | 0.89 | KCNA3 (0.56) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL5353009 | 0.89 | KCNA3 (0.56) | KCNA3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253328-A1 | Cycloalkyl inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2010-11-24 | — | — | EP | disclosed |