Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30383214 | 0.96 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL25196754 | 0.96 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL30383937 | 0.96 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL25196269 | 0.96 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL25265053 | 0.95 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL25191013 | 0.95 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL30383871 | 0.95 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL28639721 | 0.95 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL10609463 | 0.93 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL10612814 | 0.93 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294732-B | Pharmaceutical compound for treating liver diseases and application thereof | 江苏新元素医药科技有限公司 | 2021-10-26 | — | — | CN | disclosed |