Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 10/20 | 0.70 |
| ▸ | MEF2D | Q14814 | 9/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | TNKS | O95271 | 1/20 | 0.61 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 3/20 | 0.59 |
| ▸ | MMP2 | P08253 | 3/20 | 0.59 |
| ▸ | MMP9 | P14780 | 3/20 | 0.59 |
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21221175 | 0.91 | HDAC4 (0.80) | HDAC4MEF2DFFAR1EP300 | |
| SCHEMBL21221174 | 0.91 | HDAC4 (0.80) | HDAC4MEF2DFFAR1EP300 | |
| SCHEMBL24046635 | 0.89 | HDAC4 (0.69) | HDAC4MEF2DFFAR1EP300 | |
| SCHEMBL21232320 | 0.83 | HDAC4 (1.00) | HDAC4MEF2DEP300 | |
| SCHEMBL10456019 | 0.81 | HDAC4 (0.75) | HDAC4MEF2DFFAR1HDAC1HDAC3 | |
| Cinnamic Acid SCHEMBL890441 | 0.79 | HCAR2 (0.76) | HDAC4FFAR1HDAC1HDAC3HDAC2 | |
| SCHEMBL1068653 | 0.79 | FFAR1 (0.55) | HDAC4MEF2DFFAR1HDAC1MMP1 | |
| Cinnamic Acid SCHEMBL3406486 | 0.78 | HCAR2 (1.00) | HDAC4FFAR1HDAC1HDAC3HDAC2 | |
| Cinnamic Acid SCHEMBL50466 | 0.78 | HCAR2 (1.00) | HDAC4FFAR1HDAC1HDAC3HDAC2 | |
| Cinnamic Acid SCHEMBL653827 | 0.78 | HCAR2 (1.00) | HDAC4FFAR1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |