Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22122214 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL22122433 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL22122243 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL10095347 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL22128385 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL22122364 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2GAAALDH1A1KMT2ANPSR1 | |
| SCHEMBL22122424 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL22122211 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAALDH1A1KMT2ANPSR1 | |
| SCHEMBL28657765 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAALDH1A1KMT2ANPSR1 | |
| SCHEMBL22122410 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | disclosed |