SCHEMBL2864907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8256757	0.90	MAPK1 (0.54)	MAPK1SMN1; SMN2MAPK3KDRFLT3
	SCHEMBL8258494	0.83	KDM4E (0.51)	MAPK1HPGDMAPK3TP53FLT3
	SCHEMBL8257907	0.82	KDM4E (0.55)	MAPK1HPGDMAPK3FLT3CSNK1D
	SCHEMBL8257912	0.81	MAPK1 (0.49)	MAPK1MAPK3FLT3CSNK1D
	SCHEMBL8268058	0.81	KDM4E (0.52)	MAPK1HPGDMAPK3TP53FLT3
	SCHEMBL8253993	0.80	CSNK1D (0.54)	MAPK1MAPK3KDRFLT3CSNK1D
	SCHEMBL2872714	0.80	ITK (0.48)	MAPK1SMN1; SMN2NPC1MAPK3RAB9A
	SCHEMBL8258574	0.80	MAPK1 (0.49)	MAPK1MAPK3KDRCSNK1D
	SCHEMBL2861677	0.80	KMT2A (0.51)	HPGDTSHRTP53FLT3
	SCHEMBL8257894	0.79	FLT3 (0.47)	MAPK1HPGDMAPK3FLT3CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.