SCHEMBL28649404

SCHEMBL28649404

C=CCC1(CC=C)c2ccccc2-c2ccc(C(=O)C(C)=NO)cc21

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PDK2 Q15119 13/20 0.39
PGR P06401 2/20 0.35
APEX1 P27695 1/20 0.34
HTR7 P34969 2/20 0.33
HTR2B P41595 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18481742 0.86 PDK2 (0.36) POLBMAPTSMN1; SMN2PDK2PGR
SCHEMBL30617329 0.85 POLB (0.43) POLBMAPTSMN1; SMN2PDK2APEX1
SCHEMBL29089351 0.85 POLB (0.43) POLBMAPTSMN1; SMN2PDK2APEX1
SCHEMBL18235861 0.85 POLB (0.43) POLBMAPTSMN1; SMN2PDK2APEX1
SCHEMBL18235864 0.81 PDK2 (0.41) POLBMAPTSMN1; SMN2PDK2APEX1
SCHEMBL18481767 0.81 PDK2 (0.34) PDK2PGRAPEX1HTR7HTR2B
SCHEMBL28649978 0.80 KDM4E (0.40) MAPTSMN1; SMN2PDK2PGRAPEX1
SCHEMBL18481745 0.78 PDK2 (0.32) PDK2PGR
SCHEMBL18235871 0.78 POLB (0.46) POLBMAPTSMN1; SMN2PDK2HTR7
SCHEMBL18012644 0.78 MAPT (0.48) POLBMAPTSMN1; SMN2PDK2HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137443-B Fluorene derivative, photopolymerization initiator containing same, and photoresist composition 克美 2021-06-08 CN disclosed